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泛素激活酶2B重組兔單抗

簡要描述：Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes

  • 產(chǎn)品型號：bsm-62449R
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時間：2025-03-03
  • 訪  問  量： 229

詳細(xì)介紹

Human
WB,IHC-P,IHC-F,ICC/IF,IF
Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.

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